| Pair Name | Aloin, Cisplatin | ||
| Phytochemical Name | Aloin (PubChem CID: 12305761 ) | ||
| Anticancer drug Name | Cisplatin (PubChem CID: 5702198 ) | ||
| Structure of Phytochemical |
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2D
MOL
3D
MOL
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| Structure of Anticancer Drug |
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2D
MOL
3D
MOL
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| Pair Name | Aloin, Cisplatin | |||
| Disease Info | [ICD-11: 2C30] | Melanoma | Investigative | |
| Gene Regulation | Up-regulation | Expression | TG2 | hsa7052 |
| Up-regulation | Expression | TYR | hsa7299 | |
| In Vitro Model | B16-F10 | Mouse melanoma | Mus musculus (Mouse) | CVCL_0159 |
| Result | The results suggest that aloin possesses antineoplastic and antimetastatic properties, exerted likely through the induction of melanoma cell differentiation. | |||
| No. | Title | Href |
|---|---|---|
| 1 | Aloin enhances cisplatin antineoplastic activity in B16-F10 melanoma cells by transglutaminase-induced differentiation. Amino Acids. 2013 Jan;44(1):293-300. doi: 10.1007/s00726-011-1166-x. | Click |
